drugset / Trial / NCT06860373

LIFE-DSR-Biomarker Sub-study of Biomarkers in Down Syndrome Related Alzheimer's Disease (DS-AD)

NCT06860373

Phase 3 Terminated 5 enrolled LuMind IDSC Foundation
NaSingle-groupOpen-labelDiagnostic

Summary

This is an optional sub-study that will enroll participants from the LIFE-DSR parent protocol. Participants will undergo assessments at two timepoints, including: additional blood samples for PBMC and RNA extraction, as well as a lumbar puncture for collection of CSF, and/or MRI and tau PET imaging. Sub-study visits will be scheduled around a similar calendar-day as the parent protocol study visits (e.g., Month (M) 0 (M0) and M16, or M16 and M32).

Timeline

Start
2023-06-27
Primary completion
2024-04-17
Completion
2024-04-17

Drugs

EvaluationDrugModalityDoseRoute
Subject 18F-MK-6240 Diagnostic / imaging agent 185 mbq Intravenous

Indications