drugset / Trial / NCT06864169

A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)

NCT06864169

Phase 2 Active not recruiting 160 enrolled Merck Sharp & Dohme LLC Daiichi Sankyo · collab
NaSingle-groupOpen-labelTreatment

Summary

Researchers are looking for new ways to treat certain types of advanced gastrointestinal (GI) cancers. The study medicine raludotatug deruxtecan (also called MK-5909, R-DXd, or DS-6000a) is a type of medicine called an antibody-drug conjugate (ADC). An ADC attaches to a protein on cancer cells and delivers treatment to destroy those cells. The main goal of this study is to learn if the cancer responds to treatment (gets smaller or goes away).

Timeline

Start
2025-04-01
Primary completion
2026-08-18
Completion
2029-01-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Raludotatug Deruxtecan Other / unclassified Intravenous