drugset / Trial / NCT06866548

Safety and Efficacy Evaluation of Anti IGF-1R Monoclonal Antibody Combined With Anti-PD-1 Monoclonal Antibody in Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer

NCT06866548

Phase 0 Active not recruiting 7 enrolled Shanghai Changzheng Hospital
NaSingle-groupOpen-labelTreatment

Summary

This trial is designed to evaluate the safety and efficacy of anti-IGF-1R mAb in combination with anti-PD-1 mAb in patients with mCRPC.

Timeline

Start
2025-03-10
Primary completion
2025-11-11
Completion
2028-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Teprotumumab Monoclonal antibody 20 mg/kg Intravenous
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous