drugset / Trial / NCT06866600
IPSC-CMs Combined with LVAD or CABG for the Treatment of Heart Failure
RandomizedParallel-groupSingle-blindTreatment
Summary
This clinical trial investigates the safety, feasibility, and therapeutic potential of a combined approach using HiCM-188 cardiomyocyte injection delivered intramyocardially alongside either LVAD implantation or CABG surgery in patients with advanced ischemic heart failure.
Timeline
- Start
- 2025-03
- Primary completion
- 2027-12
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | HiCM-188 | Cell therapy | 5e+07 cells | Intramuscular |
| Subject | HiCM-188 | Cell therapy | 1.5e+08 cells | Intramuscular |