drugset / Trial / NCT06866691

Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

NCT06866691

Phase 4 Recruiting 600 enrolled Wake Forest University Health Sciences
RandomizedParallel-groupSingle-blindPrevention

Summary

The purpose of this study is to assess the incidence of early post-traumatic seizures. The study will also assess the benefit of lacosamide compared to levetiracetam in regards to agitation and behavioral adverse effects in patients with traumatic brain injury requiring seizure prophylaxis.

Timeline

Start
2025-04-18
Primary completion
2027-04
Completion
2027-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Lacosamide Other / unclassified 200 mg Intravenous
Subject Levetiracetam Other / unclassified 1000 mg Intravenous