Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease

Summary

The goal of this clinical trial is to evaluate the safety and potential efficacy of the EN-374 treatment regimen and identify a dose level for further evaluation in participants with x-linked chronic granulomatous disease. The main questions it aims to answer are: * safety of the EN-374 treatment regimen * effect of the EN-374 treatment regimen on the production of functional neutrophils with NADPH oxidase activity

Timeline

Start

2025-08-05

Primary completion

2027-12

Completion

2027-12

Drugs

Indications