drugset / Trial / NCT06878248

A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer

NCT06878248 ↗

Phase 1 Terminated 10 enrolled Calibr, a division of Scripps Research
NaSequentialOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate CLBR001 and ABBV-461 as a treatment for patients with locally advanced or metastatic breast cancer. The goals are to establish the safety and efficacy of the combination therapy while establishing the optimal biologic doses. Patients will be administered a single infusion of CLBR001 cells followed by cycles of ABBV-461 with regular assessments of safety and disease response to treatment.

Timeline

Start
2025-04-17
Primary completion
2026-04-09
Completion
2026-04-09

Outcome

Outcome not reported

Stopped (Business): “Business Decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject ABBV-461 Protein / enzyme biologic — —
Subject CLBR001 Cell therapy — —