drugset / Trial / NCT06880289

Chemo-Radiotherapy Boost Treatment Guided by Perfusion MRI on Hypoxic Zones in Head and Neck Cancer

NCT06880289 ↗

Phase 2 Active not recruiting 91 enrolled Regina Elena Cancer Institute
RandomizedSingle-groupOpen-labelDiagnostic

Summary

To assess and localize hypoxic tumor subregions both at baseline and during the second week of radiotherapy. And to hypothesize that an intensified IMRT regimen may ensure higher local response rates compared to the standard IMRT approach.

Timeline

Start
2020-09-16
Primary completion
2024-07-31
Completion
2027-07-31

Drugs

EvaluationDrugModalityDoseRoute
Background Cisplatin Other / unclassified 100 mg/m2 Intravenous