drugset / Trial / NCT06880549

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

NCT06880549 ↗

Phase 1 Active not recruiting 42 enrolled ModernaTX, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to assess the safety and tolerability of mRNA-4106 monotherapy and of mRNA-4200 in combination with checkpoint inhibitor therapy in participants with solid tumors.

Timeline

Start
2025-03-25
Primary completion
2027-08-03
Completion
2027-08-03

Drugs

EvaluationDrugModalityDoseRoute
Subject mRNA-4106 Unknown — Intramuscular
Subject mRNA-4200 Unknown — Intramuscular
Background Pembrolizumab Monoclonal antibody — Intravenous

Indications