drugset / Trial / NCT06883162

Cannabis-Tobacco Co-Use Treatment Study

NCT06883162

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of the RECLAIM study is to evaluate the effectiveness of varenicline (sometimes known as Chantix) compared to placebo (an inactive substance) for the treatment of cigarettes and cannabis (marijuana). Varenicline is not FDA approved for the combination treatment of cigarette abstinence and cannabis reduction or abstinence. All participants will also receive counseling and access to online treatment modules during a quit attempt for cigarettes and a reduction attempt for cannabis. This study is being conducted by the Medical University of South Carolina. All procedures are conducted remotely and there is no in-person visits are needed. To qualify, participants must be 18 or older, live in South Carolina, use cigarettes and cannabis, and are interested in quitting cigarettes and reducing cannabis.

Timeline

Start
2025-05-06
Primary completion
2028-09-01
Completion
2029-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Varenicline Small molecule 2 mg