The Pharmacokinetics Study of Fotagliptin in Patients with Different Degrees of Renal Insufficiency

Summary

The trial was designed in a single dose, open, non-randomized, multi-dose parallel control group. The study of patients were mild and moderate renal insufficiency, and matched healthy subjects.

Timeline

Start

2022-03-15

Primary completion

2022-11-01

Completion

2022-11-01

Publications

• Chen Y, Hu C, Cao X, Men Y, Wang Y, Zhang R, Guan H, Shi L, Liu F, Miao J. Pharmacokinetics, Pharmacodynamics and Safety of Fultagliptin Benzoate Tablets, a DPP-4 Inhibitor, in Patients With Varying Degrees of Renal Insufficiency and Matched Healthy Volunteers: A Phase I Clinical Trial. Clin Pharmacokinet. 2026 Apr;65(4):545-556. doi: 10.1007/s40262-026-01622-8. Epub 2026 Feb 9.

Drugs

Indications