drugset / Trial / NCT06892054
Sotorasib Combined With First-line Chemotherapy for Advanced Pancreatic Adenocarcinoma
Phase 1
Recruiting
15 enrolled
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)
Apices Soluciones S.L. · collabGERCOR - Multidisciplinary Oncology Cooperative Group · collab
NaSingle-groupOpen-labelTreatment
Summary
The main objective of this trial is to evaluate the safety and tolerability of sotorasib combined with first-line chemotherapy for advanced pancreatic adenocarcinoma harboring KRAS p.G12C mutation.
Timeline
- Start
- 2025-08-08
- Primary completion
- 2030-08-08
- Completion
- 2030-08-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sotorasib | Small molecule | 960 mg | Oral |