drugset / Trial / NCT06893250

Orthobiologic Treatment for Knee Osteoarthritis

NCT06893250

Phase 2/3 Enrolling by invitation 160 enrolled University Hospital of North Norway
RandomizedFactorialDouble-blindTreatment

Summary

The goal of this randomized clinical trial is to compare treatment for osteoarthritis in the knee using platelet rich plasma (PRP) or adipose stem cells (ADS). The main questions it aims to answer are: * Will the patients clinically benefit from the treatment, and if so, which treatment is better? * Will there be radiological findings to support this? Participants will be randomized into one of four groups: PRP, ADS, PRP + ADS or placebo treatment (saline) and will be examined and get an X-ray and MRI of the knee taken at inclusion and after 1 and 2 years.

Timeline

Start
2024-09-23
Primary completion
2027-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Platelet Rich Plasma Other / unclassified Other
Comparator Prochymal® Cell therapy Other

Indications