drugset / Trial / NCT06897202

A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM

NCT06897202

Phase 2 Completed 133 enrolled Pfizer
RandomizedParallel-groupDouble-blindTreatment

Summary

This study is designed to test how well once-weekly MET097 (an ultra-long-acting GLP-1 receptor agonist) works to treat adults with obesity or overweight and type 2 diabetes mellitus (T2DM) compared to placebo. MET097 or placebo will be administered to individuals via subcutaneous injection once weekly for 28 weeks. If an individual is randomly assigned to MET097 they will receive one of four different dose regimens.

Timeline

Start
2025-03-14
Primary completion
2025-12-29
Completion
2026-03-18

Drugs

EvaluationDrugModalityDoseRoute
Subject MET097 Peptide Subcutaneous