drugset / Trial / NCT06898957

Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC)

NCT06898957

Phase 1 Active not recruiting 29 enrolled Amgen MediLink · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

The primary objective of this study is to evaluate the safety and tolerability of tarlatamab in combination with YL201 with or without anti-PD-L1.

Timeline

Start
2025-05-16
Primary completion
2031-06-23
Completion
2031-06-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody Intravenous
Subject Tarlatamab Protein / enzyme biologic Intravenous
Subject YL201 Other / unclassified Intravenous