drugset / Trial / NCT06900725
Low Dose Edoxaban in Elderly Patients With AF and a History of Stroke
Phase 2/3
Not yet recruiting
300 enrolled
National Taiwan University Hospital
National Taiwan University Hospital Hsin-Chu Branch · collabNational Taiwan University Hospital, Yun-Lin Branch · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
This prospectively enrolled, pragmatic randomized trial aims to investigate whether very low dose edoxaban regimen (15 mg daily) achieves similar edoxaban concentrations as low dose edoxaban regimen (30 mg daily), while maintaining a comparable risk of clinical outcomes and reducing major bleeding in elderly patients with atrial fibrillation and a history of ischemic stroke or transient ischemic attack.
Timeline
- Start
- 2025-04-01
- Primary completion
- 2030-12-31
- Completion
- 2030-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Edoxaban | Small molecule | 15 mg | — |
| Comparator | Edoxaban | Small molecule | 30 mg | — |