Clinical Research on the Use of Immune Checkpoint Inhibitors Combined With Chidamide for the Functional Cure of AIDS

NCT06902038 ↗

Not yet recruiting 33 enrolled Jun Chen, MD

RandomizedParallel-groupSingle-blindTreatment

Summary

Evaluate the efficacy and safety of immune checkpoint inhibitors combined with chidamide as an "activate and kill" strategy to extend viral rebound time, reduce the HIV reservoir, and achieve functional cure.

Timeline

Start: 2025-03-22
Primary completion: 2025-12-01
Completion: 2027-12-31

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sidarbenamide	Unknown	10 mg	Oral
Subject	Sindilizumab	Unknown	100 mg	—

Clinical Research on the Use of Immune Checkpoint Inhibitors Combined With Chidamide for the Functional Cure of AIDS

Summary

Timeline

Drugs

Indications