drugset / Trial / NCT06903065

A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver Fibrosis

NCT06903065

Phase 1 Active not recruiting 50 enrolled Hoffmann-La Roche
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity and activity of RO7790121 in participants with advanced metabolic dysfunction-associated steatohepatitis (MASH) fibrosis.

Timeline

Start
2025-04-14
Primary completion
2026-09-30
Completion
2026-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Afimkibart Monoclonal antibody Intravenous

Indications

No indication recorded.