drugset / Trial / NCT06903377

Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer

NCT06903377

Phase 1/2 Recruiting 50 enrolled Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a multicenter Phase I/II study for patients with advanced non-small cell lung cancer who have failed PD-1/L1 therapy, aiming to evaluate the safety of ZG005 in combination with Gecacitinib in this population, as well as the preliminary efficacy of this combination regimen.

Timeline

Start
2025-05-23
Primary completion
2027-04
Completion
2027-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Gecacitinib Unknown 50 mg Oral
Subject Gecacitinib Unknown 100 mg Oral
Subject ZG005 Unknown 20 mg/kg Intravenous