drugset / Trial / NCT06905197

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)

NCT06905197

Phase 1 Recruiting 140 enrolled Dizal Pharmaceuticals
RandomizedSequentialOpen-labelTreatment

Summary

This study is designed to evaluate safety and anti-tumor activity of DZD6008 in patients with advanced NSCLC with EGFR mutations.

Timeline

Start
2025-05-13
Primary completion
2027-09
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject DZD6008 Unknown 20 mg Oral
Subject DZD6008 Unknown 40 mg Oral
Subject DZD6008 Unknown 60 mg Oral
Subject DZD6008 Unknown 90 mg Oral
Subject DZD6008 Unknown 120 mg Oral
Subject DZD6008 Unknown 150 mg Oral
Subject Sunvozertinib Small molecule