drugset / Trial / NCT06905496
Apnea of Prematurity Results in Respiratory Distress and Cyanosis. Caffeine Citrate Can Treat It.
RandomizedParallel-groupSingle-blindTreatment
Summary
High-dose caffeine citrate is more effective than low-dose caffeine citrate in the treatment of apnea of prematurity (AOP). The high-dose group showed fewer apnea episodes, higher extubation success rate, lower extubation failure rate and shorter duration of oxygen therapy
Timeline
- Start
- 2024-06-03
- Primary completion
- 2025-12-01
- Completion
- 2026-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Caffeine | Small molecule | 10 mg/kg | — |
| Subject | Caffeine | Small molecule | 20 mg/kg | — |