drugset / Trial / NCT06917157
Latency Antibiotics for Previable Rupture Of Membranes Trial
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to see if the use of prophylactic antibiotics in the expectant management of PPROM less than 22 weeks significantly reduce the rate of delivery within 7 days and to see if the use of prophylactic antibiotics in the expectant management of PPROM between 20 and 22 weeks decrease composite neonatal morbidity.
Timeline
- Start
- 2025-05-01
- Primary completion
- 2026-05-31
- Completion
- 2027-05-31
Outcome
Outcome not reported
Stopped (Enrollment): “PI has decided to end study due to changes in Texas law and no participants were enrolled”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin | Other / unclassified | 500 mg | Oral |
| Subject | Ampicillin | Small molecule | 2 g | Intravenous |
| Subject | Azithromycin | Small molecule | 1 g | Oral |