drugset / Trial / NCT06919991
Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)
NaSingle-groupOpen-labelBasic science
Summary
The purpose of the study is to assess the effects of multiple doses of itraconazole (a strong CYP3A4 inhibitor) on single dose PK of casdatifan in healthy adults and to assess the effects of multiple doses of phenytoin (a strong CYP3A4 inducer) on single dose PK of casdatifan in healthy adults.
Timeline
- Start
- 2025-05-02
- Primary completion
- 2025-10-18
- Completion
- 2025-10-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Casdatifan | Small molecule | — | — |
| Subject | Itraconazole | Small molecule | — | — |
| Subject | Phenytoin | Unknown | — | — |
Indications
No indication recorded.