drugset / Trial / NCT06920043

A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

NCT06920043 ↗

Phase 2 Recruiting 42 enrolled GlaxoSmithKline
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of efimosfermin in participants with metabolic dysfunction associated steatohepatitis (MASH) and compensated cirrhosis consistent with stage F4 fibrosis.

Timeline

Start
2025-04-09
Primary completion
2028-07-10
Completion
2028-07-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Efimosfermin Protein / enzyme biologic — Subcutaneous