drugset / Trial / NCT06922097

Treating Intraoperative Bradycardia in Non-cardiac Surgery Patients With Atropine at Heart Rates Below 60 Versus 30 Beats Per Minute and Norepinephrine Requirements

NCT06922097

Completed 186 enrolled University of Hamburg-Eppendorf
RandomizedParallel-groupSingle-blindTreatment

Summary

The RAPID trial is a randomized, single-center trial investigating whether giving atropine at heart rates below 60 beats per minute versus giving atropine only at heart rates below 30 beats per minute reduces the amount of norepinephrine needed to keep MAP above 65 mmHg in non-cardiac surgery patients with intraoperative bradycardia.

Timeline

Start
2025-04-07
Primary completion
2025-11-11
Completion
2025-12-16

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atropine Other / unclassified 0.5 mg

Indications

No indication recorded.