drugset / Trial / NCT06924606

Evaluating the Preliminary Efficacy and Safety of JS207 in NSCLC After Progression Following Platinum-based Chemotherapy and Immunotherapy

NCT06924606

Phase 2 Recruiting 66 enrolled Shanghai Junshi Bioscience Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multiple-arm, open phase II clinical trial evaluating the safety, tolerability,and preliminary efficacy of JS207 in NSCLC after progression following Platinum-based chemotherapy and immunotherapy.

Timeline

Start
2025-07-15
Primary completion
2026-06-26
Completion
2026-06-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 75 mg/m2
Subject JS207 Monoclonal antibody 10 mg/kg
Subject Tifcemalimab Monoclonal antibody 200 mg