drugset / Trial / NCT06925737
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
RandomizedParallel-groupOpen-labelTreatment
Summary
Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinatamab deruxtecan (also called I-DXd or MK-2400) to treat mCRPC. The goal of this study is to learn if people who receive I-DXd live longer overall and live longer without the cancer growing or spreading than people who receive chemotherapy.
Timeline
- Start
- 2025-05-13
- Primary completion
- 2028-06-26
- Completion
- 2031-01-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Docetaxel | Small molecule | 75 mg/m2 | Intravenous |
| Subject | Ifinatamab Deruxtecan | Other / unclassified | 12 mg/kg | Intravenous |
| Comparator | Prednisone | Other / unclassified | 10 mg | Oral |