Metabolic Effects of Endogenous Bile Acids After Gastric Bypass Surgery

Summary

Non-randomized, open-label, parallel-group clinical study evaluating the effects of endogenous bile acids on changes in plasma fibroblast growth factor-19 (FGF-19) and glucose metabolism by extended depletion of circulating bile acids using colesevelam as an experimental tool in subjects operated with gastric by-pass (RYGB).

Timeline

Start

2024-05-02

Primary completion

2027-12

Completion

2028-12

Drugs

Indications