drugset / Trial / NCT06927076

Antidepressant Response of DMT Masked With Propofol

NCT06927076

Recruiting 112 enrolled University Hospital, Basel, Switzerland
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The aim of this study is to elucidate if the anti-depressive effect of N,N-dimethyltryptamine (DMT) is based on a biological mechanisms including neuroplasticity and anti-inflammatory effect or due to the subjective psychedelic experience.

Timeline

Start
2025-08-05
Primary completion
2029-03
Completion
2029-03

Drugs

EvaluationDrugModalityDoseRoute
Subject N,N-Dimethyltryptamine Unknown 40 mg