drugset / Trial / NCT06928246
The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis
Non-randomizedSequentialOpen-labelOther
Summary
The purpose of this study is to understand cellular and molecular interactions in the skin of participants with mild-to-moderate AD, and how botulinum toxin alters these interactions.
Timeline
- Start
- 2025-07-17
- Primary completion
- 2026-12-15
- Completion
- 2027-01
Publications
- Background Popescu MN, Beiu C, Iliescu MG, Mihai MM, Popa LG, Stanescu AMA, Berteanu M. Botulinum Toxin Use for Modulating Neuroimmune Cutaneous Activity in Psoriasis. Medicina (Kaunas). 2022 Jun 16;58(6):813. doi: 10.3390/medicina58060813.
- Background Khattab FM. Evaluation of Botulinum Toxin A as an Optional Treatment for Atopic Dermatitis. J Clin Aesthet Dermatol. 2020 Jul;13(7):32-35. Epub 2020 Jul 1.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 50 iu | Other |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 75 iu | Other |