drugset / Trial / NCT06929702
Precision Dosing of Beta-lactam Antibiotics in Critically Ill Children
RandomizedParallel-groupDouble-blindTreatment
Summary
The overall objective of this study is to investigate the impact of early model-informed precision dosing (MIPD) on target attainment of three beta-lactam antibiotics (amoxicillin-clavulanic acid, piperacillin-tazobactam and meropenem) in critically ill children. This evaluation includes a comparison with the more standard approach on clinical and patient-oriented measures.
Timeline
- Start
- 2025-07-09
- Primary completion
- 2027-10-01
- Completion
- 2027-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin clavulanic acid | Unknown | — | — |
| Subject | Meropenem | Small molecule | — | — |
| Subject | Piperacillin-tazobactam | Unknown | — | — |
Indications
No indication recorded.