drugset / Trial / NCT06932848

The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus

NCT06932848

Recruiting 30 enrolled Chulalongkorn University
RandomizedParallel-groupDouble-blindTreatment

Summary

This randomized, double-blind clinical trial evaluates the therapeutic effects of curcumin in nanogels compared to 0.1% fluocinolone acetonide oral paste in the management of atrophic-erosive oral lichen planus (OLP). The study aims to determine whether curcumin nanogels, a natural treatment with enhanced bioavailability, are as effective and better tolerated than standard corticosteroid therapy.

Timeline

Start
2025-06-01
Primary completion
2026-06-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Curcumin Small molecule Topical
Comparator fluocinolone acetonide Small molecule 0.1 % Topical

Indications