drugset / Trial / NCT06934889

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

NCT06934889

Phase 1 Recruiting 60 enrolled Memorial Sloan Kettering Cancer Center
RandomizedParallel-groupOpen-labelTreatment

Summary

The researchers are doing this study to find out whether the drugs ABBV-637 and ABBV-155 are safe treatments that cause few or mild side effects when given alone or in combination with ERAS-801 in people with recurrent GBM.

Timeline

Start
2025-04-07
Primary completion
2028-04
Completion
2028-04

Drugs

EvaluationDrugModalityDoseRoute
Subject ABBV-637 Unknown Intravenous
Subject ERAS-801 Small molecule Oral
Subject MIRZOTAMAB CLEZUTOCLAX Unknown Intravenous
Background Temozolomide Small molecule

Indications