drugset / Trial / NCT06938503

AG Plus Nimotuzumab Sequential Irreversible Electroporation Ablation for Locally Advanced Pancreatic Cancer

NCT06938503

Phase 2 Not yet recruiting 48 enrolled Tianjin Medical University Cancer Institute and Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, open-label, single arm clinical study. The main purpose of the study is to evaluate the clinical efficacy and safety of nab-paclitaxel/gemcitabine combined with nimotuzumab sequential irreversible electroporation ablation for locally advanced pancreatic cancer. The main endpoint is overall survival (OS).

Timeline

Start
2025-04-21
Primary completion
2028-04-25
Completion
2028-04-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 1000 mg/m2
Subject Nimotuzumab Monoclonal antibody 400 mg
Subject Paclitaxel Small molecule 125 mg/m2