A Study to Evaluate the Effect of Formulation and Food on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-011)

Phase 1 Completed 52 enrolled Merck Sharp & Dohme LLC

RandomizedCrossoverOpen-labelBasic science

Summary

This study has 2 parts. Researchers want to learn what happens to calderasib in a healthy person's body over time in both parts. The goals of the study are: * In Part 1, to compare what happens to calderasib in a person's blood when it is taken as 2 different types of oral tablets * In Part 2, to learn what happens to calderasib in a person's blood when it is taken on an empty stomach or after a meal

Timeline

Start: 2025-05-13
Primary completion: 2025-06-22
Completion: 2025-08-04

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Calderasib	Unknown	—	Oral

Indications

No indication recorded.