drugset / Trial / NCT06947265
Safety And Efficacy Of L-Arginine Monotherapy Versus Tadalafil Monotherapy Versus Their Combination In Men With Erectile Dysfunction; A Prospective Randomized Study
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Introduction Sexual dysfunctions are annoying health problems with the erectile problems forming the main part of them. Erectile dysfunction (ED) is defined as the persistent inability to obtain or maintain an erection that is sufficient to allow satisfactory sexual intercourse.\[1\] Aim of Work To evaluate the role of L-arginine monotherapy versus Tadalafil monotherapy versus their combination for the treatment of erectile dysfunction . Patients and methods: Inclusion criteria: • Naive ( not previously treated) male patient with mild to moderate ED according to SHIM Questionnaire. Exclusion criteria: * Kidney disease or liver failure * Coronary heart disease * Peyronie's disease * Neurological disease that may related to ED
Timeline
- Start
- 2024-01-14
- Primary completion
- 2025-01-01
- Completion
- 2025-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | L-arginine | Small molecule | 3 g | Oral |
| Subject | Tadalafil | Small molecule | 5 mg | Oral |