drugset / Trial / NCT06947265

Safety And Efficacy Of L-Arginine Monotherapy Versus Tadalafil Monotherapy Versus Their Combination In Men With Erectile Dysfunction; A Prospective Randomized Study

NCT06947265

Phase 4 Completed 180 enrolled Fayoum University Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Introduction Sexual dysfunctions are annoying health problems with the erectile problems forming the main part of them. Erectile dysfunction (ED) is defined as the persistent inability to obtain or maintain an erection that is sufficient to allow satisfactory sexual intercourse.\[1\] Aim of Work To evaluate the role of L-arginine monotherapy versus Tadalafil monotherapy versus their combination for the treatment of erectile dysfunction . Patients and methods: Inclusion criteria: • Naive ( not previously treated) male patient with mild to moderate ED according to SHIM Questionnaire. Exclusion criteria: * Kidney disease or liver failure * Coronary heart disease * Peyronie's disease * Neurological disease that may related to ED

Timeline

Start
2024-01-14
Primary completion
2025-01-01
Completion
2025-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject L-arginine Small molecule 3 g Oral
Subject Tadalafil Small molecule 5 mg Oral

Indications