drugset
drugset / Trial / NCT06952608

Effect of Ciprofol on Intraoperative Hypotension in Elderly Patients Receiving Renin-angiotensin System Inhibitors

NCT06952608 ↗

Phase 4 Recruiting 140 enrolled Second Affiliated Hospital, School of Medicine, Zhejiang University
RandomizedParallel-groupTriple-blindPrevention

Summary

The prevention of intraoperative hypotension could reduce postoperative organ injury and mortality, particularly in elderly patients receiving long-term renin-angiotensin system inhibitors. Previous meta-analyses suggest that ciprofol, a novel intravenous anesthetic agent, may provide improved hemodynamic stability compared to propofol; however, its precise effects on perioperative hemodynamics remain unclear. The study will assess whether ciprofol improves perioperative hemodynamic stability in elderly patients receiving renin-angiotensin system inhibitors.

Timeline

Start
2025-04-10
Primary completion
2026-02-10
Completion
2026-04-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Cipepofol Small molecule — Intravenous
Comparator Propofol Small molecule — —

Indications

No indication recorded.