First-in-man Imaging of a New PET Radiotracer for Oxytocin Receptors

Phase 0 Completed 6 enrolled Aarhus University Hospital Tonix Pharmaceuticals, Inc. · collab

NaSingle-groupOpen-labelBasic science

Summary

The investigators will test a new positron-emitting radiotracer to determine whether it is suitable for studying the oxytocin receptor by positron emission tomography (PET) in humans. If suitable, the radiotracer will be used to study the brain and trigeminal nerve in several disorders.

Timeline

Start: 2021-04-30
Primary completion: 2022-06-30
Completion: 2022-06-30

Publications

Winterdahl M, Nielsen EN, Hansen SB, Dias AH, Vendelbo MH, Jakobsen S, Yeomans D. First-in-human intranasal [13N]oxytocin PET: evaluation of feasibility, biodistribution, and radiation dosimetry. EJNMMI Res. 2025 Nov 18;15(1):137. doi: 10.1186/s13550-025-01329-0.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	13N-Oxytocin	Unknown	—	Intranasal

Indications

No indication recorded.