drugset / Trial / NCT06961370
A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
RandomizedParallel-groupTriple-blindTreatment
Summary
The main purpose of this study is to assess the ocular and systemic safety and tolerability of RO7669330 in participants with GA secondary to AMD in at least one eye in Part 1, or both eyes in Part 2, after multiple unilateral intravitreal (IVT) doses.
Timeline
- Start
- 2025-07-16
- Primary completion
- 2027-01-03
- Completion
- 2027-01-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avacincaptad Pegol | Aptamer | 2 mg | Intravitreal |
| Subject | Pegcetacoplan | Peptide | 15 mg | Intravitreal |
| Subject | RO7669330 | Unknown | — | Intravitreal |