A Study of Fosmanogepix in Healthy Adult Chinese Subjects

Phase 1 Completed 54 enrolled Basilea Pharmaceutica Biomedical Advanced Research and Development Authority · collab

RandomizedParallel-groupQuadruple-blindBasic science

Summary

The purpose of this study was to investigate the pharmacokinetics and safety of the investigational drug fosmanogepix including its active moiety manogepix following a single dose and multiple doses (by intravenous infusion (IV) or orally) in healthy Chinese adults. The study consisted of 2 consecutive Parts (Part-1, single-dose part followed by Part-2, multiple-dose part) including a total of 54 subjects (32 subjects in Part-1 and 22 subjects in PART-2) randomized.

Timeline

Start: 2025-04-14
Primary completion: 2025-07-15
Completion: 2025-07-15

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Fosmanogepix	Small molecule	—	Oral

Indications

No indication recorded.