drugset / Trial / NCT06962332

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

NCT06962332

Phase 1 Recruiting 20 enrolled Exelixis
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The primary purpose of this study is to evaluate the plasma PK of zanzalintinib following a single dose in participants with moderate liver dysfunction compared to matched healthy participants with normal liver function.

Timeline

Start
2025-05-13
Primary completion
2025-12
Completion
2026-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Zanzalintinib Small molecule Oral

Indications

No indication recorded.