Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

Phase 2 Not yet recruiting 20 enrolled University of California, San Diego

RandomizedCrossoverQuadruple-blindTreatment

Summary

This research study is being conducted to see if coenzyme Q10 (a nutritional supplement) might help to prevent and/or alleviate symptoms and health consequences and help to improve quality of life and physical function in residents affected by the February 2023 East Palestine, Ohio train derailment. This is a pilot study that is not powered to achieve benefit but seek to examine effect size and variance to aid in power calculations for a potential future better powered study.

Timeline

Start: 2026-05-15
Primary completion: 2028-10-01
Completion: 2028-10-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Coenzyme Q10	Other / unclassified	100 mg	Oral

Indications

No indication recorded.