drugset / Trial / NCT06967610

Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).

NCT06967610

Non-randomizedSingle-groupOpen-labelTreatment

Summary

To learn if the drug combination pirtobrutinib, venetoclax, and obinutuzumab can help to control relapsed CLL/SLL.

Timeline

Start
2025-07-15
Primary completion
2031-06-01
Completion
2033-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Obinutuzumab Monoclonal antibody 100 mg Intravenous
Subject Pirtobrutinib Other / unclassified 200 mg Oral
Subject Venetoclax Small molecule Oral