drugset / Trial / NCT06973291
A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis
RandomizedParallel-groupDouble-blindTreatment
Summary
The main aim of this study is to assess whether zasocitinib works better than deucravacitinib in treating participants with moderate-to-severe plaque psoriasis. Participants will take one tablet daily of either zasocitinib or a matching placebo, along with one capsule daily of either over-encapsulated deucravacitinib or a matching placebo, for a duration of 16 weeks. Participants will be in the study for up to 25 weeks, which includes screening period of up to 35 days, a 16-week treatment period, and a 4-week safety follow-up period.
Timeline
- Start
- 2025-07-09
- Primary completion
- 2026-04-22
- Completion
- 2026-04-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | CRAVACITINIB | Small molecule | 6 mg | Oral |
| Subject | Zasocitinib | Small molecule | — | Oral |