The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia

Summary

Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing self-harm. Carbamazepine (CBZ) is the first-line medication for TN, yet it presents adverse effects such as addiction and the absence of analgesic effects upon cessation. Acupuncture, particularly electroacupuncture（EA）, has demonstrated efficacy in TN treatment, although its therapeutic outcomes are influenced by various factors. Consequently, this study aims to evaluate the clinical efficacy of EA for TN and its potential as an alternative to CBZ treatment.

Timeline

Start

2026-03-01

Primary completion

2028-12-31

Completion

2028-12-31

Publications

• Chen N, Xu M, Wang J, Wang D, Luo K, Hao YB, Chen K, Yang X, Ren H, Fang J, Wu Y. Effect of Electroacupuncture for Trigeminal Neuralgia: Study Protocol for a Multicenter Randomized Controlled Trial. J Pain Res. 2026 Jun 3;19:616735. doi: 10.2147/JPR.S616735. eCollection 2026.

Drugs

Indications