drugset / Trial / NCT06982131
A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants
RandomizedCrossoverDouble-blindBasic science
Summary
This is a randomized, investigator-and-participant-blind, placebo-controlled, fixed sequence, cross-over, Phase 1 study to investigate the safety, tolerability, and pharmacokinetics of multiple doses of orally administered RO7795081 and the effect of a steady-state dose of orally administered RO7795081 on the pharmacokinetics of pitavastatin and rosuvastatin in otherwise healthy, overweight or obese adult participants.
Timeline
- Start
- 2025-06-04
- Primary completion
- 2026-12-04
- Completion
- 2026-12-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pitavastatin | Small molecule | 1 mg | — |
| Subject | RO7795081 | Unknown | — | Oral |
| Subject | Rosuvastatin | Small molecule | 10 mg | — |