drugset / Trial / NCT06985472

Orelabrutinib Combined With Zuberitamab in the Initial Treatment of MZL

NCT06985472

Phase 2 Recruiting 33 enrolled Li Zhiming
NaSingle-groupOpen-labelTreatment

Summary

This is a multi-center, prospective cohort study. The main purpose of study is to evaluate the efficacy and safety of Orelabrutinib combined with Zuberitamab in the initial treatment of MZL Main efficacy indicators Complete response rate (CR) at the end of combination therapy.

Timeline

Start
2024-11-13
Primary completion
2025-12-01
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Orelabrutinib Small molecule 150 mg Oral
Subject Zuberitamab Monoclonal antibody 375 mg/m2 Intravenous