drugset / Trial / NCT06986057

Iparomlimab and Tuvonralimab Combined With Platinum-Based Chemotherapy for Neoadjuvant Treatment of Cervical Cancer

NCT06986057

Phase 2 Not yet recruiting 28 enrolled Shandong Tumor Hospital
NaSingle-groupOpen-labelTreatment

Summary

The primary objective of this study is to evaluate the efficacy and safety of Iparomlimab and tuvonralimab (QL1706) in combination with platinum-based chemotherapy for cervical cancer neoadjuvant therapy. Additionally, the study aims to identify potential predictive biomarkers for therapeutic efficacy by analyzing tumor tissues and peripheral blood samples from participants receiving this combined treatment regimen.

Timeline

Start
2025-05-31
Primary completion
2026-07-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Iparomlimab Monoclonal antibody
Subject Tuvonralimab Monoclonal antibody

Indications