drugset / Trial / NCT06990620

TACE Plus Ivonescimab for Unresectable Non-Metastatic HCC

NCT06990620

Phase 1 Not yet recruiting 56 enrolled Fudan University
NaSingle-groupOpen-labelTreatment

Summary

This study is a single-arm, multicenter, prospective clinical trial designed to evaluate the efficacy and safety of Transarterial Chemoembolization (TACE) combined with envafolimab in patients with unresectable, non-metastatic hepatocellular carcinoma (HCC), while exploring potential biomarkers associated with treatment response.

Timeline

Start
2025-06
Primary completion
2027-06
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ivonescimab Monoclonal antibody 20 mg/kg Intravenous