Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery

Recruiting 30 enrolled Ain Shams University

RandomizedParallel-groupDouble-blindPrevention

Summary

This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes following spinal anesthesia.

Timeline

Start: 2025-06-01
Primary completion: 2025-10-01
Completion: 2025-11-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ketamine	Small molecule	0.5 mg/kg	Intravenous

Indications

No indication recorded.